Using your new 12-inch hybrid queen mattress is a breeze. Once you unpack it from the box, place it on your bed frame - whether it's a foundation or slatted support. Just make sure to give it 48 to 72 hours to fully expand. During this time, don't sleep on it right away to let it reach its full potential. When it comes to maintenance, keep the mattress clean by vacuuming it regularly. If there are any spills, clean them up immediately with a mild detergent and a damp cloth. Avoid using harsh chemicals as they might damage the fabric or the foam. For a longer lifespan, rotate the mattress every few months. This will help prevent uneven wear. And remember, this mattress is not only for regular beds but also great for RVs and adjustable bed frames. Enjoy a restful and comfortable sleep every night!